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Apr 11, 2026 - Rīga Stradiņš University
Irmejs, Arvīds; Loža, Pēteris; Maksimenko, Jeļena; Daneberga, Zanda; Liepiņa, Elza Elizabete; Čerņeikina, Anneta, 2026, "Development of Genetic Testing Strategies for Hereditary Breast and Ovarian Cancer Risk Prediction by Analysis of Spectrum of Predisposing Mutations and Their Phenotypic Manifestations: Clinical Data", https://doi.org/10.48510/FK2/AJIIVR, UNF:6:lYl2b0nqg1ects0ji1GdSg== [fileUNF]
The clinical data of retrospective cohort were collected to calculate Manchester score and CanRisk tool value for all breast and ovarian cancer cases. The NGS targeted panel including 9 genes was performed for samples with previously negative genetic testing results and available biological material. Pathogenicity of genetic variants were classifie...
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